Product name: 10-Hydroxy Camptothecin
CAS No.: 19685-09-7
Formula: C20H16N2O5
Molecular weight: 364.34
Structure:
Melting Point: 268-270℃
Introduction:
10-Hydroxycamptothecin, the derivative of camptothecin, is a minor alkaloid isolated from Camptotheca acuminata (a tree native to mainland China), At present, as an alkaloid anticancer, It is the only known natural DNA Topo isomerase inhibitors. Soluble in methanol, chloroform, acetonitrile; insoluble in water, Its sodium salt is soluble in water, its organic solution has blue fluorescence.
Specification:
Appearance: Yellow crystal
Active ingredient content, %: 99 min.
Pharmacological activity: Anti-cancer activity
Indication: Anti-cancer drug, suitable for treatment of breast and rectum cancers, liver cancer, stomach cancer, malignant melanoma, small-cell lung cancer and leukemia.
Side effects: The major side effects of hydroxycamptothecin are potentially severe diarrhea, nausea, lowered leukocyte (white blood cell) counts and also damage bone marrow, but much less than camptothecin.
Packing: 10g/Tin, 50g/Tin
Storage: Store in cool and dry place, keep tightly closed
Period of Validity: 3 Years
