Lisinopril
CAS:83915-83-7
Chemical name:(S)-1-(N2-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate
Appearance
White crystalline powder
Conforms
Solubility
Very soluble in water, sparingly soluble in methanol, practically insoluble in acetone and ethanol
Conforms
Specific rotation
-115.3°- -122.5°
-119.0°
Water
8.0%-9.0%
8.5%
Residue on ignition
≤ 0.1%
0.05%
Heavy metals
≤0.001%
Conforms
Related substances
R.S.S.-1 somer≤0.3%
N2-(1-carboxy-3-phenylpropyl)-l-lysine≤0.1%
Diketopiperazine≤0.3%
Cyclohexyl lisinopril≤0.3%
Single impurity ≤0.1%
Total impurities ≤0.5%
ND
0.07%
ND
ND
Conforms
0.06%
Incrosial limit test:
Total aerobic microbial≤500CFU/g
Total combined microbial ≤1000CFU/g
Yeasts and molds
Escherichina coli
Salmonella species
Conforms
Conforms
ND
ND
Assay
98.5%-101.5%
99.44%
